The last part of the chapter includes a brief description of various benign as well as malignant lesions, the pathological as well as the etiological aspects and the hormonal abnormalities associated. The chapter also includes various genetic syndromes that are associated with the disorders associated with hormones of adrenal cortex. Thus this chapter includes the disease that are related to excess as well as deficiencies of the hormones secreted by adrenal cortex. So it is very important as a part of a clinician as well as a pathologist to know the pattern in which these hormones are secreted along with their physiological roles. Also it is very infrequent to encounter metastatic lesions in the adrenal glands too. Lesions of adrenal cortex are quite common to encounter and most of these are related to the hormones secreted by three layers of adrenal cortex: the zona glomerulosa, the zona fasciculata, and the zona reticularis. These secrete various hormones that have a vital role in maintaining the normal homeostasis of the body. Adrenal gland is an endocrine organ comprising of an outer cortex and inner medulla.
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